A nanoscale balance for individual cells

An interdisciplinary team from the University of Basel, ETH Zurich, and University College London have developed a new method that can be used to analyze individual live mammalian cells within a cell assembly. Based on a system of tiny cantilever probes, the technique records the cell mass over several days in millisecond steps and is accurate to within a few picograms. Using the new technique, the scientists have been able to observe for the first time that the cell mass fluctuates within the space of a few seconds. These findings and the new platform provide fundamental insights into the regulation of cell mass and into how this is disrupted in the event of illness. The study was presented today in the journal Nature.

 

Originalbeitrag:

Nature 550, 500–505, (26 October 2017)
doi:10.1038/nature24288, http://www.nature.com/nature/journal/v550/n7677/full/nature24288.html

Weitere Informationen:
Prof. Dr. Christoph Gerber, Swiss Nanoscience Institute, Klingelbergstrasse 82, 4056 Basel
+41 61 207 3737, christoph.gerber@unibas.ch

Prof. Dr. Daniel Müller, Department of Biosystems Science and Engineering, ETH Zürich in Basel, Mattenstrasse 26, 4058 Basel
+41 61 387 3307, daniel.mueller@bsse.ethz.ch